NASA's Glory (http://glory.giss.nasa.gov/) spacecraft launched aboard a Taurus XL rocket from Vandenberg Air Force Base in California Friday at 5:09:45 a.m. EST failed to reach orbit.
Telemetry indicated the fairing, the protective shell atop the Taurus XL rocket, did not separate as expected about three minutes after launch.
More: http://www.nasa.gov/mission_pages/Glory/main/index.html
This launch also carried three CubeSats (http://www.scientificcomputing.com/news-DS-NASA-Cues-up-CubeSats-for-Glory-Launch-012910.aspx), all of which are presumably somewhere in the Pacific...
...and some detail about the launch (http://blogs.howstuffworks.com/2011/03/04/yesterdays-death-of-the-nasas-glory-satellite-cubesat-status-unknown/).